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1.
Rev. bras. otorrinolaringol ; 72(5): 609-616, set.-out. 2006. ilus, graf, tab
Article in Portuguese | LILACS | ID: lil-439839

ABSTRACT

O presente trabalho refere-se ao estudo dos resultados clínicos e histológicos obtidos após a turbinectomia inferior parcial (TIP), cirurgia indicada no tratamento da obstrução nasal crônica causada pela hipertrofia das conchas nasais inferiores. MATERIAL E MÉTODOS: Foram estudados vinte pacientes, divididos em dois grupos de dez cada (grupos A e B), submetidos à TIP, associada à septoplastia ou não. Os pacientes foram reavaliados clinicamente e histologicamente (com biópsia das áreas regeneradas das conchas inferiores), em dois períodos pós-operatórios diferentes: um grupo após oito a doze meses (grupo A) e outro após dois anos de TIP (grupo B). RESULTADOS: Os resultados clínicos mostraram-se satisfatórios para o alívio da obstrução nasal no grupo A, e insatisfatórios no grupo B. Entretanto, melhores resultados histológicos, com maior recuperação e diferenciação epitelial da mucosa regenerada das conchas inferiores após a TIP foram observados no grupo B, com sua ultraestrutura ciliar normal. CONCLUSÕES: A cirurgia revelou ser eficaz a curto, mas não em médio prazo, apesar da recuperação histológica ter sido importante.


We report clinical and histological results obtained after partial inferior turbinectomy (PIT), surgery indicated for the treatment of chronic nasal obstruction. METHODS: Twenty patients were divided into two groups submitted to PIT plus septoplasty and PIT alone. The patients were reassessed clinically and histologically by means of a biopsy of the regenerated areas in the inferior turbinates at two different times after PIT, i.e., after 8 to 12 months (group A) and after two years (group B). RESULTS: The clinical results proved to be satisfactory for the relief of nasal obstruction in group A and unsatisfactory in group B. However, better histological results with better recovery and epithelial differentiation of the regenerated mucosa of the inferior turbinates after PIT were observed in group B. CONCLUSION: Surgery proved to be effective on a short-term but not on a long-term basis, and histological recovery did not accompany improvement of clinical signs and symptoms.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Nasal Mucosa/ultrastructure , Nasal Obstruction/surgery , Nasal Septum/surgery , Turbinates/surgery , Chronic Disease , Follow-Up Studies , Microscopy, Electron, Scanning , Nasal Septum/ultrastructure , Treatment Outcome , Turbinates/ultrastructure
2.
Acta AWHO ; 16(2): 83-6, abr.-jun. 1997. ilus, tab
Article in Portuguese | LILACS | ID: lil-196317

ABSTRACT

Os aspectos histopatológicos da túnica mucosa do 1/3 médio da concha nasal inferior foram avaliados em 3 indivíduos normais, considerando como parâmetros no plano epitelial: hiperplasia, hipertrofia, necrose, metaplasia escamosa e atrofia; no plano da lâmina própria: alteraçöes vasculares, infiltrado inflamatório, fibrose da lâmina própria, espessamento da membrana basal; no plano das células secretoras: aumento do número de células secretoras, aumento da secreçäo, aumento do muco neutro e do muco ácido intracelular. Foram demonstrados proliferaçäo vascular discreta da lâmina própria, ausência de ectasia linfática e marcado espessamento da membrana basal além da atrofia e de metaplasia escamosa importante.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Turbinates/anatomy & histology , Epithelium/ultrastructure , Mucous Membrane/anatomy & histology , Mucous Membrane/physiopathology , Turbinates/physiopathology , Turbinates/ultrastructure
3.
Asian Pac J Allergy Immunol ; 1993 Dec; 11(2): 103-9
Article in English | IMSEAR | ID: sea-36442

ABSTRACT

Kartagener's syndrome is a well known classical triad of presentations consisting of bronchiectasis, sinusitis and situs inversus. It is now recognized that the syndrome is an extreme presentation of primary ciliary dyskinesia, a large group of conditions with ultrastructural ciliary defects, leading to poor ciliary motility in various organ systems. A case of Kartagener's syndrome is presented in an eight year old Thai boy in whom the ultrastructural ciliary defects have been examined and described in detail for the first time in Thailand. Incomplete lack of dynein arms was recognized. In addition, disorientation of ciliary axis was noticed. Due to severe bronchiectatic changes of the right lower lobe and right lingular lobe which did not improve despite adequate antibiotics, these lobes were surgically removed. The child has done well since, but still suffers occasional and recurrent bouts of sinusitis.


Subject(s)
Child , Cilia/ultrastructure , Ciliary Motility Disorders/pathology , Epithelium/ultrastructure , Humans , Kartagener Syndrome/pathology , Male , Turbinates/ultrastructure
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